My Desktop Computer - Hard Disc Problem

For the past few months, when I boot from desktop I used to get a error CMOS\GPNV Checksum bad error, I keep pressing F4 and kept working. To resolve this problem I downloaded the latest patch from Intel for the mother board and also replaced with a new CMOS battery and suddenly Harddisc was not detectable.

I have given my harddisc to check whether it can be recovered. Hope I can recover my data from my hard disc.